Santee, South Carolina Hotels

Arrival Date
Departure Date
Adults
Children
Comfort Inn & Suites Santee
221 Britain Street
Santee, SC 29142
Nightly Rates (85.99 - 129.99)   2 Star
Comfort Inn & Suites Santee
Located in the heart of one of South Carolina's premier golfing destinations, the Comfort Inn and Suites hotel in Santee, SC is ideally located only 1.5 miles from the Santee Convention Center and with easy access to Interstate 96, perfect ...more
BEST WESTERN PLUS Santee Inn
I-95 Exit 98
Santee, SC 29142
Nightly Rates (93.59 - 99.99)   3 Star
BEST WESTERN PLUS Santee Inn
Conveniently located off I-95, this Santee hotel offers cozy guest rooms and easy access to area attractions, including golf courses and state parks.Rated number one on TripAdvisor for the Town of Santee, the BEST WESTERN PLUS Santee Inn of...more
Hampton Inn Santee-I-95
9060 Old 6 Highway
Santee, SC 29142
Nightly Rates (96.90 - 129.00)   3 Star
Hampton Inn Santee-I-95
The Hampton Inn Santee-I-95 SC hotel in South Carolina is located at I-95 Exit 98 and is a state-of-the-art interior corridor hotel with two elevators. The hotel is in the heart of Santee Cooper Country well known for excellent golf fishing...more
Holiday Inn SANTEE
139 Bradford Blvd.
Santee, SC 29142
Nightly Rates (97.35 - 119.00)   3 Star
Holiday Inn SANTEE
Santee Hotel's Address Convenient to Lake MarionGoing fishing or golfing? The Holiday InnŽ Santee hotel is perfect for both recreational activities. Just off I-95 in Santee, SC, our hotel's location is less than an hour from both Columbia a...more
Howard Johnson Inn Santee
249 Britain Street
Santee, SC 29142
Nightly Rates (45.49 - 49.49)   1 Star
Howard Johnson Inn Santee
Enjoy Southern hospitality at this Howard Johnson Inn Santee conveniently located off Interstate 95 near several golf courses, fishing and boating at Lake Marion. Stroll Santee State Park, or shop the discounts at Santee Factory Outlets. St...more
Quality Inn & Suites
8929 Old Number Six Highway
Santee, SC 29142
Nightly Rates (79.99 - 102.99)   2 Star
Quality Inn & Suites
Hotel features Golf and Fishing packages year round (call hotel direct for details), Lake Marion 1/2 mile, Carolina Grill Restaurant and Ziggy's Lounge located off hotel lobby, Free HSIA, Free USA and Local paper, Fitness Center and Hot Tub...more
Super 8 Santee
9125 Old Hwy 6
Santee, SC 29142
Nightly Rates (55.00 - 65.00)   1 Star
Super 8 Santee
Welcome to the Super 8 in Santee- located in the heart of South Carolinas best golfingMidway between New York and Florida, we are the perfect stop along the wayOutlet shopping just across the streetAll rooms are on the ground floor, wi...more
Rodeway Inn Santee
9117 Old Number 6 Hwy
Santee, SC 29142
Nightly Rates (59.99 - 69.99)   1 Star
Rodeway Inn Santee
Located in the heart of South Carolina's premier golfing destinations, the Rodeway Inn is ideally located within walking distance from two of Santee's amazing golf courses and only one-half mile from Interstate 95. All rooms feature wireles...more
Econo Lodge Santee
9112 Old Number 6 Hwy
Santee, SC 29142
Nightly Rates (54.99 - 54.99)   1 Star
Econo Lodge Santee
Located in the heart of South Carolina's premier golfing destinations, the Econo Lodge is ideally located walking distance from two of Santee's amazing golf courses and only one-half mile from Interstate 95. The hotel is perfect for both bu...more
Red Roof Inn Santee
9091 Old Highway 6
Santee, SC 29142
Nightly Rates (62.49 - 62.49)   1 Star
Red Roof Inn Santee
Welcome to Santee, a year round golf destination most well known in golf circles as, Americas Value Golf Destination. Retreat to a haven of nature and picturesque scenery in Santee, a small town with a reverence for nature on the edge of L...more


Santee Hotel Chains

Best Western

Comfort Inn

Econo Lodge

Hampton Inn

Holiday Inn

Howard Johnson

Quality Inn

Red Roof Inn

Rodeway Inn

Super 8




Santee POI

Resorts - Spas- Camping - RV Parks

Lake Marion Resort and Marina
2.78 miles