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Edisto Island, South Carolina Hotels

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Edisto Island Serpentarium - Edisto Island South Carolina
Country Hearth Inn Walterboro
33 Campground Road
Walterboro, SC 29488
Nightly Rates (33.20 - 39.95)   3 Star
34.03 miles from Edisto Island Serpentarium
Country Hearth Inn Walterboro Country Hearth Inn Walterboro
Country Hearth Inns and Suites wants to help you feel at home as much as possible when you are on the road. Experience a warm, inviting, and family-oriented lodging choice at a reasonable price at Country Hearth Inns and Suites hotels with...more
Masters Inn Charleston-North
6100 Rivers Avenue
North Charleston, SC 29406
Nightly Rates (35.00 - 39.00)  
28.27 miles from Edisto Island Serpentarium
Masters Inn Charleston-North Masters Inn Charleston-North
Masters Inn in North Charleston is located on Aviation Avenue, off I-26 at Exit 211B. It is just minutes away from the airport, the mall, outlet stores, the North Charleston Coliseum, Historic Downtown Charleston and The Citadel. Local c...more
Masters Inn Charleston Mt Pleasant
300 Wingo Way
Mount Pleasant, SC 29464
Nightly Rates (43.00 - 53.28)  
28.08 miles from Edisto Island Serpentarium
Masters Inn Charleston Mt Pleasant Masters Inn Charleston Mt Pleasant
Masters Inn Charleston-Mt. Pleasant is located just over the Cooper River Bridge off Highway 17. It is just 3 miles from historic downtown Charleston. This hotel has an outdoor swimming pool, and offers free local calls and free coffee. C...more
Days Inn Port Royal
1660 Ribaut Rd
Port Royal, SC 29935
Nightly Rates (47.97 - 57.10)   2 Star
26.71 miles from Edisto Island Serpentarium
Days Inn Port Royal Days Inn Port Royal
The Days Inn Port Royal is the closest hotel to Parris Island. We offer Free High Speed Wireless, Free Continental Breakfast, Microfridge in all rooms, Air Conditioning, Coffee Makers, Iron and Iron Board, expanded cable service with 3 HBO...more
North Charleston Inn
2934 West Montague Avenue
North Charleston, SC 29418
Nightly Rates (49.49 - 49.49)   2 Star
26.39 miles from Edisto Island Serpentarium
North Charleston Inn North Charleston Inn
Recently renovated. Convenient to all Charleston, blocks from Airport, Convention Center, Performing Arts Center, Centre Point, Tanger Outlets, The Plex. Close to Hunley, historic downtown Charleston, Mount Pleasant. Conveniently located to...more
Americas Best Inns-Beaufort
2448 Boundary St.
Beaufort, SC 29903
Nightly Rates (55.00 - 55.00)   1 Star
26.24 miles from Edisto Island Serpentarium
Americas Best Inns-Beaufort Americas Best Inns-Beaufort
Our Property Is One Of The Most Beautiful In The Area Conveniently Located Near The Historic Downtown Area, Restaurants, Shopping, Movies Are Within Walk DistanceUsmc Recruit Depot And The Marine Corps Air Station, Hilton Head Island, Golf ...more
Days Inn Mount Pleasant-Charleston-Patriots Point
261 Johnnie Dodds Blvd
Mount Pleasant, SC 29464
Nightly Rates (55.20 - 60.00)   2 Star
27.90 miles from Edisto Island Serpentarium
Days Inn Mount Pleasant-Charleston-Patriots Point Days Inn Mount Pleasant-Charleston-Patriots Point
Relax and enjoy the special Southern Hospitality that Days Inn and Charleston are famous for. The staff at Days Inn Charleston/Patriots Point are ready to serve you. The Days Inn Charleston/Patriots Point is conveniently located across the...more
Ramada Walterboro
1245 Sniders Hwy
Walterboro, SC 29488
Nightly Rates (59.49 - 59.49)   1 Star
33.45 miles from Edisto Island Serpentarium
Ramada Walterboro Ramada Walterboro
The Ramada Walterboro, South Carolina is situated off I-95 at Exit 53 Highway 63. The South Carolina Artisans Center is less then 1 mile away from the Ramada's front door. The contemporary and comfortable accommodations of the Ramada Walter...more
Econo Lodge Charleston
2237 Savannah Hwy.
Charleston, SC 29414
Nightly Rates (59.99 - 59.99)   1 Star
21.22 miles from Edisto Island Serpentarium
Econo Lodge Charleston Econo Lodge Charleston
The Econo Lodge hotel is conveniently located close to historic downtown Charleston, the North Charleston Performing Arts Center, the North Charleston Coliseum and the Charleston Area Convention Center. The College of Charleston, The Citade...more
Quality Inn & Suites
1286 Sniders Highway
Walterboro, SC 29488
Nightly Rates (61.24 - 61.24)   2 Star
33.47 miles from Edisto Island Serpentarium
Quality Inn & Suites Quality Inn & Suites
Completely renovated inside and out (2007), this hotel is the perfect place to spend the night in Walterboro. All rooms feature coffee makers, irons and ironing boards, free high-speed Internet access and cable television with HBO. Take a d...more
Days Inn Walterboro
1787 Sniders Highway
Walterboro, SC 29488
Nightly Rates (62.00 - 67.00)   2 Star
33.88 miles from Edisto Island Serpentarium
Days Inn Walterboro Days Inn Walterboro
5-Sunburst Rated for Quality Free High Speed Wireless Internet Free Continental Daybreak Breakfast Business Center in Lobby Area Micro-Fridge Rooms Available All Rooms Hairdryer, AM-FM Clock Radio Cable TV with HBO,FOX,ESPN,ESPN2,Movie Clas...more
Radisson Hotel Charleston Airport
5991 RIVERS AVENUE
Charleston, SC 29406
Nightly Rates (62.30 - 93.45)   2 Star
28.12 miles from Edisto Island Serpentarium
Radisson Hotel Charleston Airport Radisson Hotel Charleston Airport
Adjacent to Charleston Airport, Airforce Base. Convenient to outlet shopping, fine dining and attractions. Beautiful Sunlit Atrium, indoor heated pool, whirlpool and new health club. Newly renovated rooms feature sleep number beds and compl...more
Microtel Inn And Suites Walterboro
130 Cane Branch Road
Walterboro, SC 29488
Nightly Rates (63.00 - 66.00)   1 Star
33.74 miles from Edisto Island Serpentarium
Microtel Inn And Suites Walterboro Microtel Inn And Suites Walterboro
The Microtel Inn and Suites Walterboro is the areas newest discount hotel. Our convenient location is just off of Interstate 95 at Exit 53, across the street from Cracker Barrel Restaurant. This hotel has 70 rooms including single rooms wit...more
Sleep Inn Mount Pleasant
299 Wingo Way & US 17 Bypass N
Mount Pleasant, SC 29464
Nightly Rates (64.99 - 74.99)   2 Star
28.02 miles from Edisto Island Serpentarium
Sleep Inn Mount Pleasant Sleep Inn Mount Pleasant
Three story interior corridor hotel located off US 17. Complimentary continental breakfast, free local phone calls, cable w/HBO, coffeemakers, iron and ironing boards and USA Today. Close to many restaurants. 3 miles to downtown, MUSC and C...more
Sleep Inn Beaufort
2523 Boundary St.
Beaufort, SC 29902
Nightly Rates (66.67 - 79.99)   1 Star
26.34 miles from Edisto Island Serpentarium
Sleep Inn Beaufort Sleep Inn Beaufort
The Sleep Inn hotel is conveniently located in historic Beaufort, just one mile from the University of South Carolina Beaufort. This Beaufort hotel is just minutes from Hunting Island State Park, Marine Corps Air Station Beaufort, and Parri...more
Hampton Inn Hilton Head
1 Dillon Road
Hilton Head Island, SC 29926
Nightly Rates (69.00 - 119.00)   2 Star
34.17 miles from Edisto Island Serpentarium
Hampton Inn Hilton Head Hampton Inn Hilton Head
This hotel is now entirely nonsmoking and is about a 45 minute drive from Parris Island MCRD The Hampton Inn Hilton Head hotel in South Carolina is newly renovated and upgraded. The hotel is the only Hampton Inn located on Hilton Head Isla...more
Rodeway Inn Mount Pleasant
310 Highway 17 Bypass
Mount Pleasant, SC 29464
Nightly Rates (69.95 - 121.95)   1 Star
28.00 miles from Edisto Island Serpentarium
Rodeway Inn Mount Pleasant Rodeway Inn Mount Pleasant
Rodeway Inn at River Crossing is well maintained and features 115 clean, comfortable rooms equipped with microwaves, refrigerators, coffee makers, and irons and ironing boards. Guests appreciate the delicious southern breakfast served each ...more
Econo Lodge Beaufort
2227 Boundary Street
Beaufort, SC 29902
Nightly Rates (69.99 - 79.99)   1 Star
25.60 miles from Edisto Island Serpentarium
Econo Lodge Beaufort Econo Lodge Beaufort
The Econo Lodge hotel is located in the heart of the business district, six miles from Parris Island and minutes from historic downtown Beaufort. Shops, restaurants, and any other business needs you might have are within walking distance of...more
Quality Inn At Town Center
2001 Boundary Street
Beaufort, SC 29902
Nightly Rates (69.99 - 69.99)   1 Star
25.12 miles from Edisto Island Serpentarium
Quality Inn At Town Center Quality Inn At Town Center
Located in the Beaufort Town Center, the hotel is only 1/2 mile from the Historic District. With magnificent water views and moss draped live oak trees, visitors are transported back to a time when Plantations flourished. Countless activiti...more
Best Western Of Walterboro
1428 Sniders Highway
Walterboro, SC 29488
Nightly Rates (70.00 - 139.99)   2 Star
33.62 miles from Edisto Island Serpentarium
Best Western Of Walterboro Best Western Of Walterboro
Escape to historic Walterboro, South Carolina and stay at this pet-friendly hotel providing convenient access to a variety of key area attractions. Welcome to the BEST WESTERN of Walterboro where guests will enjoy true Southern hospitalit...more
La Quinta Inn & Suites Charleston Riverview
11 Ashley Pointe Drive
Charleston, SC 29407
Nightly Rates (70.00 - 95.00)   2 Star
23.83 miles from Edisto Island Serpentarium
La Quinta Inn & Suites Charleston Riverview La Quinta Inn & Suites Charleston Riverview
Overlooking the beautiful Ashley River, the newly renovated La Quinta Inn & Suites Charleston Riverview offers a variety of modern services and amenities while maintaining the rich historical character of its surroundings. Historic Downtown...more
Inn at River Crossing
310 HWY 17 BYPASS
Mount Pleasant, SC 29464
Nightly Rates (72.95 - 149.95)   2 Star
28.22 miles from Edisto Island Serpentarium
Inn at River Crossing Inn at River Crossing
The Inn at River Crossing is a two-story exterior corridor hotel located on US 17 North, across the Cooper River from historic Charleston. Locally owned by three young Charleston couples,we offer 122 comfortable rooms, warm, friendly servic...more
Howard Johnson Inn Beaufort/Parris Island
3651 Trask Parkway
Beaufort, SC 29906
Nightly Rates (75.65 - 72.82)   1 Star
27.13 miles from Edisto Island Serpentarium
Howard Johnson Inn Beaufort/Parris Island Howard Johnson Inn Beaufort/Parris Island
Beaufort, SC with over 500 years of history by the sea offers a wonderful menu for everyone. Our mild climate permits golf and fishing to be enjoyed year round. Historic downtown can be toured by land or by sea with daily carriage and boat ...more
Town And Country Inn And Conference Cent
2008 Savannah Highway
Charleston, SC 29407
Nightly Rates (79.00 - 89.00)  
21.52 miles from Edisto Island Serpentarium
Town And Country Inn And Conference Cent Town And Country Inn And Conference Cent
The Town and Country Inn and Conference Center is a suburban 3-Star AAA-Rated property in the West Ashley community four miles from the Downtown Historic District of Charleston. A full-service property catering to both corporate and socia...more
Hilton Head Island Beach And Tennis Resort
40 Folly Field Rd
Hilton Head Island, SC 29928
Nightly Rates (79.20 - 189.00)  
34.45 miles from Edisto Island Serpentarium
Hilton Head Island Beach And Tennis Resort Hilton Head Island Beach And Tennis Resort
A price within reach/ right on the beach. Youll feel right at home in any one of our 1 or 2 bedroom villas. Each with a fully equipped kitchen/ living area with sofa sleeper and bath. Ten lighted tennis courts/ olympic size pool/ kiddie poo...more
Red Roof Inn Mt Pleasant Patriots Point
301 Johnnie Dodds Blvd
Mount Pleasant, SC 29464
Nightly Rates (81.24 - 86.24)   2 Star
27.76 miles from Edisto Island Serpentarium
Red Roof Inn Mt Pleasant Patriots Point Red Roof Inn Mt Pleasant Patriots Point
Red Roof Mt. Pleasant Patriots Point, conveniently located just 4 miles from Charleston s Famous Historical District, is within minutes of The Patriots Point Maritime Museum. We re adjacent to the beautiful links of the Patriots Point Golf ...more
Comfort Inn & Suites
97 Downs Lane
Walterboro, SC 29488
Nightly Rates (84.99 - 119.99)   2 Star
33.53 miles from Edisto Island Serpentarium
Comfort Inn & Suites Comfort Inn & Suites
Check into South Carolina's only Platinum Award winning Comfort Inn & Suites and discover Southern Hospitality redefined. Our free Comfort Sunshine breakfast features hot, fresh Belgian Waffles and biscuits with sausage gravy. Our business ...more
Country Inn & Suites By Carlson Beaufort West
2450 BOUNDARY ST
Beaufort, SC 29906
Nightly Rates (87.00 - 219.33)   2 Star
26.26 miles from Edisto Island Serpentarium
Country Inn & Suites By Carlson Beaufort West Country Inn & Suites By Carlson Beaufort West
Convenient to military bases. Indoor pool and spa, fitness center, business center, free hi-speed internet access (wired and wireless); all rooms include microwave, fridge, iron and ironing board, hair dryer, HBO, CNN, ESPN, free breakfast,...more
Sleep Inn & Suites Convention Center
4715 Saul White Blvd
North Charleston, SC 29418
Nightly Rates (89.95 - 136.62)   2 Star
26.46 miles from Edisto Island Serpentarium
Sleep Inn & Suites Convention Center Sleep Inn & Suites Convention Center
The brand new (2007) Sleep Inn and Suites is 100 percent smoke free and is located just off I-26 near the Charleston Convention Center, Tanger Outlet Mall and the Charleston International Airport. The Sleep Inn features modern amenities suc...more
Quality Inn Coliseum
5055 North Arco Lane
North Charleston, SC 29418
Nightly Rates (89.99 - 94.99)   2 Star
26.63 miles from Edisto Island Serpentarium
Quality Inn Coliseum Quality Inn Coliseum
Tanger Outlet Mall is within walking distance 200 yards with 18 restuarants with-in 1/2 mile. Historic District 9 miles and beaches 17-19 miles. International Airport 4 miles. Charleston Coliseum within 1/2 mile. Free deluxe continental ...more
Hawthorn Suites by Wyndham Charleston
2455 Savannah Hwy
Charleston, SC 29414
Nightly Rates (93.05 - 110.13)   2 Star
20.92 miles from Edisto Island Serpentarium
Hawthorn Suites by Wyndham Charleston Hawthorn Suites by Wyndham Charleston
Welcome to Charleston, South Carolinas newest Hawthorn Suites by Wyndham. This extended stay hotel in Charleston just opened in 2006 to bring travelers one of the best hotels in the Savannah Highway area. Conveniently located within seven m...more
Super 8 Beaufort/Paris Island
1360 South Ribaut Rd
Port Royal, SC 29935
Nightly Rates (94.99 - 109.99)   1 Star
26.15 miles from Edisto Island Serpentarium
Super 8  Beaufort/Paris Island Super 8  Beaufort/Paris Island
Welcome to the Super 8 of Port Royal, a close hotel to Parris Island. Make us your home away from home while visiting South Carolinas famous Low Country beaches and historic sites. Great rates for visiting US Military families. We feature ...more
Days Inn Charleston- Airport Coliseum
2998 West Montague Ave
North Charleston, SC 29418
Nightly Rates (95.95 - 92.95)   1 Star
26.32 miles from Edisto Island Serpentarium
Days Inn Charleston- Airport Coliseum Days Inn Charleston- Airport Coliseum
Located near I-26 and I-526 Historic Charleston just 7 Miles down Interstate Highway N. Charleston Coliseum Performing Arts Center - 2 Blocks N. Charleston Convention Center - 2 Blocks Beaches - 15 minutes Plantations - 15 minutes Charlesto...more
Holiday Inn Hotel & Suites BEAUFORT @ HIGHWAY 21
2225 BOUNDARY STREET
Beaufort, SC 29902
Nightly Rates (96.77 - 128.97)   2 Star
25.56 miles from Edisto Island Serpentarium
Holiday Inn Hotel & Suites BEAUFORT @ HIGHWAY 21 Holiday Inn Hotel & Suites BEAUFORT @ HIGHWAY 21
Welcome to the Holiday Inn Beaufort. You'll discover true Southern hospitality at the Holiday Inn Beaufort, nestled in the heart of South Carolina's Lowcountry. The Holiday Inn Beaufort is located on Boundary Street/Highway 21, just one mil...more
Holiday Inn Express Hotel & Suites WALTERBORO I-95
1834 SNIDERS HIGHWAY
Walterboro, SC 29488
Nightly Rates (97.00 - 107.00)   2 Star
33.84 miles from Edisto Island Serpentarium
Holiday Inn Express Hotel & Suites WALTERBORO I-95 Holiday Inn Express Hotel & Suites WALTERBORO I-95
Welcome to the newly opened Holiday Inn Express Hotel & Suites of Walterboro, SC . We are conveniently located at the junction of Interstate-95 and SC Highway 63 (Exit 53). We are only 45 minutes away from Charleston, SC , one hour from Sav...more
Hampton Inn Beaufort
2342 Boundary Street
Beaufort, SC 29902
Nightly Rates (98.10 - 129.00)   2 Star
25.96 miles from Edisto Island Serpentarium
Hampton Inn Beaufort Hampton Inn Beaufort
The Hampton Inn Beaufort hotel in South Carolina is located one block south of the intersection of Hwy. 170 and US Hwy. 21 behind Applebee*s Restaurant. The hotel is one mile from downtown three miles from Beaufort Municipal Airport and fo...more
Best Western Sweetgrass Inn
1540 Savannah Highway
Charleston, SC 29407
Nightly Rates (98.75 - 98.75)   2 Star
22.16 miles from Edisto Island Serpentarium
Best Western Sweetgrass Inn Best Western Sweetgrass Inn
Stay at this Charleston hotel -located just minutes from historic downtown, plantations and Fort Sumter, free Internet. The BEST WESTERN Sweetgrass Inn is committed to providing the best in customer service and accommodations at an afforda...more
Holiday Inn CHARLESTON-MT. PLEASANT
250 JOHNNY DODDS BLVD.
Mount Pleasant, SC 29464
Nightly Rates (99.00 - 126.00)   3 Star
27.85 miles from Edisto Island Serpentarium
Holiday Inn CHARLESTON-MT. PLEASANT Holiday Inn CHARLESTON-MT. PLEASANT
Welcome to One of the Finest Hotels in Mt. Pleasant, SC If you're looking for hotels near Charleston, SC with Southern hospitality and charm, you've found it. The renovated Holiday Inn hotel of Charleston - Mount Pleasant offers quality am...more
Days Inn Charleston- Historic District
155 Meeting Street
Charleston, SC 29401
Nightly Rates (99.00 - 109.00)   2 Star
25.32 miles from Edisto Island Serpentarium
Days Inn Charleston- Historic District Days Inn Charleston- Historic District
The Days Inn Historic Charleston. Located in the Center of Historic Charleston. Across the street from the Famous Open Market. Within easy walking distance of the Historic Attractions. Walking Distance of Downtown Charleston. Walk to 40 of ...more
Holiday Inn Express Hotel & Suites MT PLEASANT-CHARLESTON
350 JOHNNIE DODDS BOULEVARD
Mount Pleasant, SC 29464
Nightly Rates (99.00 - 114.00)   2 Star
28.05 miles from Edisto Island Serpentarium
Holiday Inn Express Hotel & Suites MT PLEASANT-CHARLESTON Holiday Inn Express Hotel & Suites MT PLEASANT-CHARLESTON
Our Mt Pleasant, SC Hotel's Rooms Go Green See Charleston, South Carolina at its best when you stay at the smoke-free Holiday Inn Express & Suites Mt. Pleasant - Charleston . Located at the foot of the Arthur Ravenel Jr. Bridge, just off Hw...more
Hampton Inn Walterboro
1835 Sniders Highway
Walterboro, SC 29488
Nightly Rates (99.00 - 99.00)   2 Star
33.94 miles from Edisto Island Serpentarium
Hampton Inn Walterboro Hampton Inn Walterboro
The Hampton Inn Walterboro hotel in South Carolina is located off I-95 and Highway 63 only 3.5 miles from beautiful historic downtown Walterboro SC and the South Carolina Artisan Center and eight miles to Meadowlake Brook Gardens. Dining o...more
Hampton Inn CharlestonMt PleasantPatriots
255 Johnnie Dodds Blvd Hwy 17N
Mt. Pleasant, SC 29464
Nightly Rates (99.74 - 132.34)   2 Star
28.11 miles from Edisto Island Serpentarium
Hampton Inn CharlestonMt PleasantPatriots Hampton Inn CharlestonMt PleasantPatriots
In addition to the room and tax rate quoted please be aware that a 1.00USD per night per room Destination Fee will be applied at check out. The Hampton Inn Charleston/Mt. Pleasant-Patriots Point hotel is 2 miles from downtown Charleston So...more
Holiday Inn Express CHARLESTON US HWY 17 & I-526
1943 SAVANNAH HIGHWAY
Charleston, SC 29407
Nightly Rates (101.16 - 101.16)   2 Star
21.66 miles from Edisto Island Serpentarium
Holiday Inn Express CHARLESTON US HWY 17 & I-526 Holiday Inn Express CHARLESTON US HWY 17 & I-526
Charleston, SC Hotel's Convenience and Value are Perfect The Holiday Inn Express Charleston US Hwy 17 & I-526 is one of Charleston's most conveniently situated hotels. We are located just five miles from downtown historic Charleston, and s...more
Hilton Garden Inn Beaufort
1500 Queen St.
Beaufort, SC 29902
Nightly Rates (103.20 - 179.00)   2 Star
25.24 miles from Edisto Island Serpentarium
Hilton Garden Inn Beaufort Hilton Garden Inn Beaufort
The Hilton Garden Inn Beaufort hotel located in beautiful historic Beaufort South Carolina is just 1 mile from the historic district downtown and 3 miles from Parris Island. The hotel is convenient to the historic district and near all mili...more
Hampton Inn Suites CharlestonWest Ashley
655 Citadel Haven Drive
Charleston, SC 29414
Nightly Rates (105.40 - 134.00)   2 Star
21.36 miles from Edisto Island Serpentarium
Hampton Inn  Suites CharlestonWest Ashley Hampton Inn  Suites CharlestonWest Ashley
In addition to the room and tax rate quoted please be aware that a 1.00 USD per night per room Destination Fee will be applied at check out. The Hampton Inn - Suites Charleston/West Ashley hotel is located off Hwy. 17 within minutes of His...more
Quality Inn & Suites Patriots Point
196 Patriots Point Rd
Mount Pleasant, SC 29464
Nightly Rates (106.66 - 146.66)   2 Star
27.59 miles from Edisto Island Serpentarium
Quality Inn & Suites Patriots Point Quality Inn & Suites Patriots Point
Located at Patriots Point. Three miles to the Charleston Historical District, four miles to area beaches. Golf course adjacent. Whirlpool suites available. Free full hot breakfast buffet. City - Patriots Point...more
Courtyard Charleston North/Coliseum
2415 Mall Drive,Interstate 26 and Montague Avenue
North Charleston, SC 29406
Nightly Rates (109.00 - 159.00)   3 Star
26.78 miles from Edisto Island Serpentarium
Courtyard Charleston North/Coliseum Courtyard Charleston North/Coliseum
This Courtyard hotel in North Charleston, South Carolina is centrally located between Interstates 26 & 526 and 3 miles from the International Airport (CHS). Spend the day in historic Charleston or at the Tanger Outlet mall while staying at ...more
Fairfield Inn & Suites Charleston Airport/Convention Center
4841 Tanger Outlet Blvd
North Charleston, SC 29418
Nightly Rates (112.00 - 169.00)   2 Star
26.59 miles from Edisto Island Serpentarium
Fairfield Inn & Suites Charleston Airport/Convention Center Fairfield Inn & Suites Charleston Airport/Convention Center
Only Fairfield Inn & Suites by Marriott?? gives you confidence that your trip will be a success because we consistently deliver a hotel experience that's just right. We provide you with just what you need, and skip what you don't, so travel...more
Comfort Suites Beaufort
131 Big John Rd.
Beaufort, SC 29906
Nightly Rates (112.49 - 140.62)   2 Star
26.74 miles from Edisto Island Serpentarium
Comfort Suites Beaufort Comfort Suites Beaufort
Welcome to the brand new 2007 Comfort Suites, located in the heart of historic Beaufort. Hotel is a perfect fit for business travelers, military families or a weekend getaway. Restaurants, shops, historic sites, leisure activities and great...more
Best Western Patriots Point
259 Mcgrath Darby Boulevard
Mount Pleasant, SC 29464
Nightly Rates (112.50 - 112.50)   2 Star
27.89 miles from Edisto Island Serpentarium
Best Western Patriots Point Best Western Patriots Point
Discover this charming Mount Pleasant, South Carolina hotel located minutes away from Charleston area attractions. Welcome to the BEST WESTERN Patriots Point Inn where guests will find true southern hospitality, charming accommodations an...more
Hampton Inn CharlestonDaniel Island SC
160 Fairchild Street
Charleston, SC 29492
Nightly Rates (118.15 - 214.00)   2 Star
30.04 miles from Edisto Island Serpentarium
Hampton Inn CharlestonDaniel Island SC Hampton Inn CharlestonDaniel Island SC
The Hampton Inn Charleston-Daniel Island hotel is located at Exit 24 I-526 on Daniel Island South Carolina. This is the newest developed area of Charleston and home of the Family Circle Cup a Tier One women*s tennis tournament. Area attra...more
MainStay Suites Mount Pleasant
400 McGrath Darby Blvd
Mount Pleasant, SC 29464
Nightly Rates (119.00 - 189.00)   2 Star
28.01 miles from Edisto Island Serpentarium
MainStay Suites Mount Pleasant MainStay Suites Mount Pleasant
The Mainstay Suites Mt. Pleasant is located at the base of the Arthur Ravenel Bridge adjacent to Patriots Point. Property is within easy access of the historic district of downtown Charleston and the beaches. Historic plantations, Mt. Pleas...more
Holiday Inn CHARLESTON-RIVERVIEW
301 SAVANNAH HWY
Charleston, SC 29407
Nightly Rates (119.00 - 132.00)   3 Star
23.83 miles from Edisto Island Serpentarium
Holiday Inn CHARLESTON-RIVERVIEW Holiday Inn CHARLESTON-RIVERVIEW
Stay Your Way at the Holiday Inn Charleston-Riverview This amazing Charleston, SC hotel's location is perfect for business and leisure travelers looking for lodging near some of the city's best attractions, restaurants and shopping. Whethe...more
Aloft Charleston Airport & Convention Center
4875 Tanger Outlet Boulevard
Charleston, SC 29418
Nightly Rates (119.00 - 129.00)   3 Star
26.51 miles from Edisto Island Serpentarium
Aloft Charleston Airport & Convention Center Aloft Charleston Airport & Convention Center
Aloft hotels are the new twist in travel from Starwood Hotels & Resorts. A vision of W Hotels, the aloft Charleston Airport & Convention Center is a bold, fresh, and fun new hotel featuring loft-inspired design and always-abuzz public spac...more
Quality Inn & Suites
200 Museum Street
Hilton Head Island, SC 29926
Nightly Rates (119.00 - 179.00)   2 Star
35.47 miles from Edisto Island Serpentarium
Quality Inn & Suites Quality Inn & Suites
A resort hotel without resort prices offers full-service hotel with huge luxury rooms and suites with all modern amenities including wireless internet access, refrigerator and microwave in every room, free deluxe continental breakfast, free...more
Kiawah Island Golf Resort
12 Kiawah Beach Drive
Kiawah Island, SC 29455
Nightly Rates (119.00 - 440.00)   3 Star
9.39 miles from Edisto Island Serpentarium
Kiawah Island Golf Resort Kiawah Island Golf Resort
Kiawah Island Golf Resort offers one to four bedroom villas and homes nestled along 10 miles of beach. These AAA Four Diamond rated accommodations feature a spacious living room, full kitchen, dining room, separate bedrooms and a balcony or...more
Homewood Suites by Hilton Charleston Airport/Conv Center
5048 International Blvd.
Charleston, SC 29418
Nightly Rates (119.20 - 149.00)   3 Star
26.19 miles from Edisto Island Serpentarium
Homewood Suites by Hilton Charleston Airport/Conv Center Homewood Suites by Hilton Charleston Airport/Conv Center
Located in the North Area of Charleston SC our new Homewood Suites by Hilton Charleston Airport/Convention Center is just one mile from the Charleston International Airport 1/2 mile from the Charleston Area Convention Center Complex and 1/4...more
Sleep Inn Charleston
1524 Savannah Hwy (US 17 S)
Charleston, SC 29407
Nightly Rates (119.99 - 119.99)   2 Star
22.17 miles from Edisto Island Serpentarium
Sleep Inn Charleston Sleep Inn Charleston
Come stay in our beautifully decorated rooms, featuring free high-speed Internet access, irons, ironing boards, coffee makers, hair dryers, free HBO, ceiling fans, and much more. Free continental breakfast with Belgian waffles. Swimming ava...more
Main Street Inn
2200 Main Street
Hilton Head Island, SC 29926
Nightly Rates (120.00 - 150.00)   2 Star
35.22 miles from Edisto Island Serpentarium
Main Street Inn Main Street Inn
Conviently located on the Northside of Hilton Head Island This European Inn, one of Hilton Head's 'Best Kept' Secrets, is a tranquil enclave from the rest of the world filled with the most lavish amentities found in a modern premier hotel. ...more
Hampton Inn CharlestonAirport/Coliseum
4701 Saul White Boulevard
North Charleston, SC 29418
Nightly Rates (122.40 - 149.00)   2 Star
26.49 miles from Edisto Island Serpentarium
Hampton Inn CharlestonAirport/Coliseum Hampton Inn CharlestonAirport/Coliseum
The Hampton Inn Charleston-Airport/Coliseum hotel in South Carolina is less than a mile from the North Charleston Coliseum and the Charleston Performing Arts Center 2.5 miles from Charleston International Airport and the Charleston Air Forc...more
Comfort Inn Charleston
144 Bee St.
Charleston, SC 29401
Nightly Rates (123.33 - 149.99)   1 Star
24.49 miles from Edisto Island Serpentarium
Comfort Inn Charleston Comfort Inn Charleston
Whether on business or pleasure, our beautiful 7-story hotel is the perfect location for you. Close to Historic Charleston and within 1 mile of MUSC, VA Hospital, and Citadel. All rooms include microwaves, refrigerators, coffee, hair dryer,...more
Best Western Plus Charleston Downtown Hotel
146 Lockwood Drive
Charleston, SC 29403-5102
Nightly Rates (124.99 - 325.00)   2 Star
24.52 miles from Edisto Island Serpentarium
Best Western Plus Charleston Downtown Hotel Best Western Plus Charleston Downtown Hotel
Experience the charm of Southern hospitality and legendary guest service at this Charleston hotel, only minutes from Charleston's famous Historic District. Our restaurant has a new and exciting look and serves full hot breakfast. The BES...more
Embassy Suites North Charleston - Airport/Hotel & Convention Center
5055 International Blvd.
North Charleston, SC 29418
Nightly Rates (125.10 - 149.00)   3 Star
26.14 miles from Edisto Island Serpentarium
Embassy Suites North Charleston - Airport/Hotel & Convention Center Embassy Suites North Charleston - Airport/Hotel & Convention Center
The Embassy Suites North Charleston SC hotel is located adjacent to the North Charleston Area Convention Center the North Charleston Coliseum and the North Charleston Performing Arts Center only two miles from the Charleston International A...more
Crowne Plaza CHARLESTON AIRPORT - CONV CTR
4831 TANGER OUTLET BOULEVARD
North Charleston, SC 29418
Nightly Rates (126.00 - 126.00)   3 Star
26.69 miles from Edisto Island Serpentarium
Crowne Plaza CHARLESTON AIRPORT - CONV CTR Crowne Plaza CHARLESTON AIRPORT - CONV CTR
Experience North Charleston Hotel's Low Country Charm At the Crowne Plaza Hotel Charleston Airport - Convention Center, patrons encounter a genuine Southern experience. Each room is outfitted with every imaginable comfort, and the hotel's ...more
Hampton Inn Suites Charleston/MtPleasantIsle Of Palms
1104 Isle of Palms Connector
Mt. Pleasant, SC 29464
Nightly Rates (126.65 - 159.00)   2 Star
32.58 miles from Edisto Island Serpentarium
Hampton Inn  Suites Charleston/MtPleasantIsle Of Palms Hampton Inn  Suites Charleston/MtPleasantIsle Of Palms
In addition to the room and tax rate quoted please be aware that a 1.00USD per night per room Destination Fee will be applied at check out. The Hampton Inn - Suites Charleston/Mt. Pleasant-Isle of Palms hotel in South Carolina is located n...more
Holiday Inn CHARLESTON AIRPORT & CONV CTR
5264 INTERNATIONAL BLVD
North Charleston, SC 29418
Nightly Rates (129.00 - 159.00)   3 Star
25.72 miles from Edisto Island Serpentarium
Holiday Inn CHARLESTON AIRPORT & CONV CTR Holiday Inn CHARLESTON AIRPORT & CONV CTR
North Charleston Hotel Offers Upscale Accommodations Welcome to the Holiday Inn hotel in North Charleston, SC. Our upscale amenities and convenient location near Charleston International Airport (CHS) and the Charleston Convention Center m...more
Residence Inn Charleston Downtown/Riverview
90 Ripley Point Drive
Charleston, SC 29407
Nightly Rates (129.00 - 199.00)   3 Star
23.68 miles from Edisto Island Serpentarium
Residence Inn Charleston Downtown/Riverview Residence Inn Charleston Downtown/Riverview
Residence Inn by Marriott Charleston Downtown/Riverview is just 1.5 miles from the Historic District and is close to SPAWAR, Boeing, Joint Base Charleston, FLETC, The Citadel, College of Charleston and MUSC. Your next business meeting will ...more
Hyatt Place Charleston Airport Conv Cntr
3234 West Montague Ave
North Charleston, SC 29418
Nightly Rates (129.00 - 134.00)   3 Star
25.94 miles from Edisto Island Serpentarium
Hyatt Place Charleston Airport Conv Cntr Hyatt Place Charleston Airport Conv Cntr
Hyatt Place is a new kind of hotel that puts style, innovation, and The Hyatt Touch with everyone's reach. Our guests enjoy a spacious guestroom with a 42-in flat panel high-definition television, signature Hyatt Grand Bed, and the plush C...more
THE LODGE ALLEY INN
195 EAST BAY STREET
Charleston, SC 29401
Nightly Rates (129.00 - 208.00)   3 Star
25.53 miles from Edisto Island Serpentarium
THE LODGE ALLEY INN THE LODGE ALLEY INN
Condo style resort units in the heart of Charleston City, Downtown...more
Plantation Oaks Inn
1199 Long Point Rd
Mount Pleasant, SC 29464
Nightly Rates (129.00 - 149.00)   2 Star
29.17 miles from Edisto Island Serpentarium
Plantation Oaks Inn Plantation Oaks Inn
Built on the historic property of what was once part of Snee Farm Plantation owned by Charles Pinckney signer of the United States Constitution, this luxurious log exterior bed and breakfast is surrounded by 300-year-old Live Oak trees and ...more
Marriott's Barony Beach Club
5 Grasslawn Avenue
Hilton Head Island, SC 29928
Nightly Rates (130.00 - 185.00)   3 Star
33.76 miles from Edisto Island Serpentarium
Marriott's Barony Beach Club Marriott's Barony Beach Club
Tucked along the beach within Hilton Head Island's acclaimed Port Royal Plantation is Marriott's Barony Beach Club. With two spacious bedrooms and bathrooms, our Hilton Head villas offer a one-of-a-kind resort experience. Enjoy splendid gar...more
Sheraton Charleston Airport Hotel
4770 Goer Drive
Charleston, SC 29406
Nightly Rates (134.10 - 164.10)   3 Star
26.78 miles from Edisto Island Serpentarium
Sheraton Charleston Airport Hotel Sheraton Charleston Airport Hotel
Welcome to the Sheraton Charleston Airport Hotel. Charleston offers something for everyone: rich history, world-class shopping, the finest Lowcountry cuisine, and so much more. We are conveniently located between the Historic Downtown Distr...more
The Society House
292 King Street
Charleston, SC 29401
Nightly Rates (134.10 - 298.80)   3 Star
25.34 miles from Edisto Island Serpentarium
The Society House The Society House
Where King and Society Streets meet, nestled in the center of historic Charleston's shopping district, this handsomely restored inn boasts nine exclusive luxury suites. With grand windows, full kitchens, and unparalleled convenience, The So...more
Comfort Suites West of the Ashley
2080 Savannah Highway
Charleston, SC 29407
Nightly Rates (136.67 - 173.33)   2 Star
21.44 miles from Edisto Island Serpentarium
Comfort Suites West of the Ashley Comfort Suites West of the Ashley
Five minutes from downtown historic Charleston, at the intersection of I-526 and US-17. Ten minutes from the Charleston International Airport, twenty minutes from Charleston's famous beaches. Abundant retail and dining options within walkin...more
Waters Edge Inn at Folly Beach
79 West 2nd Street
Folly Beach, SC 29439
Nightly Rates (138.00 - 138.00)   2 Star
20.81 miles from Edisto Island Serpentarium
Waters Edge Inn at Folly Beach Waters Edge Inn at Folly Beach
Secluded in a lush tropical setting and located minutes from Charleston, South Carolina, Waters Edge Inn boasts eight beautifully appointed guest rooms feature Heavenly queen size beds with Egyptian cotton sheets and down comforters, plasma...more
Holiday Inn CHARLESTON (HISTORIC DISTRICT)
125 Calhoun Street
Charleston, SC 29401
Nightly Rates (139.00 - 159.00)   3 Star
25.57 miles from Edisto Island Serpentarium
Holiday Inn CHARLESTON (HISTORIC DISTRICT) Holiday Inn CHARLESTON (HISTORIC DISTRICT)
Holiday Inn Charleston Historic District Hotel is named Best Hidden Gem in the World by Trip Advisor, eight year recipient of the Intercontinental Hotels Torchbearer Award and winner of the first Kemmons Wilson Spirit of Hospitality Award...more
Residence Inn Charleston Airport
5035 International Blvd.
North Charleston, SC 29418
Nightly Rates (139.00 - 139.00)   3 Star
26.18 miles from Edisto Island Serpentarium
Residence Inn Charleston Airport Residence Inn Charleston Airport
Get FREE high-speed Internet access at this Residence Inn! The award winning Residence Inn by Marriott - Charleston Airport welcomes you to the beautiful city of Charleston. Located minutes from the Charleston Airport, Charleston Conventi...more
Hampton Inn CharlestonHistoric District
345 Meeting Street
Charleston, SC 29403
Nightly Rates (139.00 - 219.00)   2 Star
25.51 miles from Edisto Island Serpentarium
Hampton Inn CharlestonHistoric District Hampton Inn CharlestonHistoric District
In addition to the room and tax rate quoted please be aware that a 1.00USD per night per room Destination Fee will be applied at check out. The Hampton Inn Charleston-Historic District hotel is located in the heart of downtown Charleston S...more
Wyndham VR Ocean Ridge
1 King Cotton Rd
Edisto Beach, SC 29438
Nightly Rates (139.00 - 139.00)   2 Star
6.04 miles from Edisto Island Serpentarium
Wyndham VR Ocean Ridge
Natural Carolina Beauty. Wyndham Ocean Ridge is located just off of South Carolina s southern coast on Edisto Island surrounded by 300 wooded acres of sleepy lagoons exotic flora and majestic birds that soothe the soul and stimulate the sen...more
Indigo Inn
1 Maiden Lane
Charleston, SC 29401
Nightly Rates (139.00 - 139.00)   3 Star
25.49 miles from Edisto Island Serpentarium
Indigo Inn Indigo Inn
The Indigo Inn offers distinctive lodging in the heart of Charlestons historic district. Located within walking distance to the open air market churches historic mansions and Charlestons finest restaurants the Indigo Inn is convenient to al...more
Hilton Head Island Beach and Tennis Resort
40 Folly Field Road
Hilton Head Island, SC 29928
Nightly Rates (139.28 - 199.28)   1 Star
34.46 miles from Edisto Island Serpentarium
Hilton Head Island Beach and Tennis Resort Hilton Head Island Beach and Tennis Resort
Hilton Head Island Beach and Tennis offers a 15,000 square foot conference center and is your ultimate destination for a fun-filled family vacation, a relaxing getaway for two, or a productive business conference in a beautiful resort setti...more
Hilton Garden Inn Charleston Airport
5265 International Blvd.
Charleston, SC 29418
Nightly Rates (142.86 - 209.00)   3 Star
25.98 miles from Edisto Island Serpentarium
Hilton Garden Inn Charleston Airport Hilton Garden Inn Charleston Airport
The Hilton Garden Inn Charleston Airport hotel is two blocks from the Charleston Convention Center Performing Arts Center and Coliseum via a scenic boardwalk and is the closest hotel to Charleston International Airport. Tanger Outlet is rig...more
Clarion Inn North Charleston
3640 Dorchester Road
North Charleston, SC 29405
Nightly Rates (143.30 - 143.30)   2 Star
26.49 miles from Edisto Island Serpentarium
Clarion Inn North Charleston Clarion Inn North Charleston
Whether you visit for business or pleasure, we have everything you need. We are ideally located just minutes from local pristine beaches, the historic sites of Charleston, and the many beautiful plantations around town. Newly renovated in J...more
The Westin Hilton Head Island Resort & Spa
Two Grasslawn Avenue
Hilton Head Island, SC 29928
Nightly Rates (149.00 - 189.00)   4 Star
33.74 miles from Edisto Island Serpentarium
The Westin Hilton Head Island Resort & Spa The Westin Hilton Head Island Resort & Spa
Located along a pristine stretch of sandy white beach, in Port Royal Plantation, The Westin Hilton Head Island Resort & Spa provides the utmost in southern hospitality. Awarded the AAA Four Diamond Award in 2008, this rejuvenating resort fe...more
Jasmine House
64 Hassell Street
Charleston, SC 29401
Nightly Rates (149.00 - 159.00)   3 Star
25.48 miles from Edisto Island Serpentarium
Jasmine House Jasmine House
The Jasmine House offers luxurious accommodations in a Southern Style. This 1843 Greek Revival mansion is located in the Ansonborough area of historic Charleston. It is within walking distance to the bustling City Market and surrounded by C...more
Kiawah Island by ResortQuest
115 Freshfields Drive
Kiawah Island, SC 29455
Nightly Rates (151.00 - 566.84)   2 Star
8.46 miles from Edisto Island Serpentarium
Kiawah Island by ResortQuest Kiawah Island by ResortQuest
Kiawah Island offers 10,000 acres of beauty. There are 10 miles of pristine beach, perfect for shelling, swimming, or just relaxing. The lush maritime forest, which lies just beyond the delicate sand dunes, is a haven for wildlife, and hero...more
Best Western King Charles Inn
237 Meeting Street
Charleston, SC 29401
Nightly Rates (152.10 - 155.67)   2 Star
25.45 miles from Edisto Island Serpentarium
Best Western King Charles Inn Best Western King Charles Inn
Experience this downtown Charleston hotel located in the heart of the historic district. This boutique hotel offers complimentary off street parking and is within walking distance to all area dining, shopping and the famous Market, Museum M...more
BEST WESTERN PLUS Sea Island Inn
1015 Bay Street
Beaufort, SC 29902
Nightly Rates (157.50 - 157.50)   2 Star
24.61 miles from Edisto Island Serpentarium
BEST WESTERN PLUS Sea Island Inn BEST WESTERN PLUS Sea Island Inn
Stay at this 100% non-smoking Beaufort, South Carolina hotel located near the Beaufort Bay, Hunting Island State Park and the Parris Island Marine Corps Depot. Welcome to the BEST WESTERN PLUS Sea Island Inn, located right across from the...more
City Loft Hotel
301 Carteret Street
Beaufort, SC 29902
Nightly Rates (159.00 - 179.00)   2 Star
24.39 miles from Edisto Island Serpentarium
City Loft Hotel City Loft Hotel
As a guest you will experience our gracious hospitality and what is new in urban hotel design. Amenities include free wifi services available throughout the facility, crisp well appointed rooms with soaking tubs, glass showers, flat screen ...more
Residence Inn Charleston Mt. Pleasant
1116 Isle of Palms Connector
Mount Pleasant, SC 29464
Nightly Rates (159.00 - 239.00)   3 Star
32.49 miles from Edisto Island Serpentarium
Residence Inn Charleston Mt. Pleasant Residence Inn Charleston Mt. Pleasant
Get FREE high-speed Internet access at this Residence Inn. Experience the splendor of the Islands at Residence Inn Charleston-Mt Pleasant. The feel of the West Indies will surround you with comfort and style! Visit the beaches on the Isl...more
Homewood Stes Mt Pleasant
1998 Riviera Drive
Mount Pleasant, SC 29464
Nightly Rates (159.20 - 233.10)   2 Star
32.55 miles from Edisto Island Serpentarium
Homewood Stes Mt Pleasant Homewood Stes Mt Pleasant
The Homewood Suites by Hilton-reg. Charleston - Mt. Pleasant hotel is conveniently located off of Hwy 17N in Mt. Pleasant SC. We are only 7.5 miles from the Charleston historic district and 1.5 miles from the Isle of Palms beach. The Home...more
Holiday Inn CHARLESTON-MILLS HOUSE
115 MEETING ST.,PO BOX 1013
Charleston, SC 29401
Nightly Rates (164.00 - 174.00)   3 Star
25.27 miles from Edisto Island Serpentarium
Holiday Inn CHARLESTON-MILLS HOUSE Holiday Inn CHARLESTON-MILLS HOUSE
Experience Our Historic Charleston Hotel's Charm Discerning travelers choose gracious Southern hospitality, Old World charm and modern amenities when they select the historic Mills House Hotel in Charleston, SC. Named to Cond Nast's 'Gold ...more
Andrew Pinckney Inn
40 Pinckney Street
Charleston, SC 39401
Nightly Rates (169.00 - 329.00)   2 Star
25.51 miles from Edisto Island Serpentarium
Andrew Pinckney Inn Andrew Pinckney Inn
Meticulously restored, the Andrew Pinckney Inn is a boutique hotel surrounded by over 300 years of history, which gracefully couples old world charm and sophisticated amenities. Overlooking the historic Charleston market area in the heart o...more
Value Place Leeds
4475 Leeds Place West
North Charleston, SC 29405
Nightly Rates (169.99 - 209.99)   2 Star
24.85 miles from Edisto Island Serpentarium
Value Place Leeds Value Place Leeds
Value Place is an extended-stay hotel. Our rates are priced for a minimum one week stay, and are not adjusted to a daily rate if the stay is less than one week. When your stay goes into the next week, another weekly rate is charged. Howeve...more
SpringHill Suites Charleston Downtown/Riverview
98 Ripley Point Drive
Charleston, SC 29407
Nightly Rates (179.00 - 179.00)   2 Star
23.78 miles from Edisto Island Serpentarium
SpringHill Suites Charleston Downtown/Riverview SpringHill Suites Charleston Downtown/Riverview
Come stay at the SpringHill Suites by Marriott Charleston Riverview, the ideal choice when traveling to Charleston for business, family vacations, or romantic getaways. Conveniently located near MUSC, Roper Hospital, United States Coast Gua...more
Comfort Suites At Isle Of Palms Connector
1130 Hungryneck Blvd.
Mount Pleasant, SC 29464
Nightly Rates (179.99 - 301.66)   2 Star
32.41 miles from Edisto Island Serpentarium
Comfort Suites At Isle Of Palms Connector Comfort Suites At Isle Of Palms Connector
The Comfort Suites at Isle of Palms Connector is just a short drive from Charleston and less than two miles from Isle of Palms beaches. An ideal place to stay while visiting the South Carolina Lowcountry, this Mount Pleasant hotel is just m...more
Value Place Charleston Rivers
4851 Rivers Avenue
Charleston, SC 29406
Nightly Rates (179.99 - 229.99)   2 Star
27.29 miles from Edisto Island Serpentarium
Value Place Charleston Rivers Value Place Charleston Rivers
Value Place offers affordable weekly stays for fully furnished studios with a full kitchen. Although many guests decide to stay with us for months, some may choose the flexible option of extending their weekly stay for additional nights. W...more
Seabrook Island by ResortQuest
115 Freshfields Dr.
Kiawah Island, SC 29455
Nightly Rates (180.00 - 196.00)  
8.46 miles from Edisto Island Serpentarium
Seabrook Island by ResortQuest Seabrook Island by ResortQuest
Seabrook Island is a private resort community just 21 miles from historic Charleston, SC. Edged by uncrowded beaches and pristine sand dunes, this beautiful island is a perfect place for a family, reunion or wedding. Guests can enjoy world...more
Courtyard Charleston Waterfront
35 Lockwood Drive
Charleston, SC 29401
Nightly Rates (189.00 - 229.00)   3 Star
24.36 miles from Edisto Island Serpentarium
Courtyard Charleston Waterfront Courtyard Charleston Waterfront
Discover one of the most luxurious hotels in downtown Charleston, SC at the Courtyard Charleston Waterfront. Experience stunning views of the Ashley River while dining, swimming in the outdoor waterfront pool or relaxing in a waterfront gue...more
The Beaufort Inn
809 Port Republic St
Beaufort, SC 29902
Nightly Rates (189.00 - 289.00)   3 Star
24.45 miles from Edisto Island Serpentarium
The Beaufort Inn The Beaufort Inn
The Beaufort Inn located one block from the Intercostals Waterway in the heart of the National Historic Landmark District of Beaufort South Carolina is a proud member of the National Trusts Historic Hotels of America. Ranked as one of the T...more
Francis Marion Hotel
387 King Street
Charleston, SC 29403
Nightly Rates (189.00 - 279.00)   3 Star
25.37 miles from Edisto Island Serpentarium
Francis Marion Hotel
Located in the heart of historic downtown Charleston on legendary King Street across from Marion Square the Francis Marion Hotel has offered gracious service and elegant accommodations since 1924. Meticulously restored the Francis Marion co...more
Charleston Battery Carriage Ho
20 South Battery
Charleston, SC 29401
Nightly Rates (189.00 - 189.00)   2 Star
25.21 miles from Edisto Island Serpentarium
Charleston Battery Carriage Ho Charleston Battery Carriage Ho
Romantic and cozy historic carriage house inn on the famous Battery Park White Point Gardens which overlooks the harbor. Elegant Small Hotels - This is definitely the right spot for a gracious, relaxing, European-style getaway south of the ...more
Battery Carriage House Inn
20 S. Battery
Charleston, SC 29401
Nightly Rates (189.00 - 259.00)   2 Star
25.00 miles from Edisto Island Serpentarium
Battery Carriage House Inn Battery Carriage House Inn
If you desire a truly Charleston Experience- nothing surpasses a stay at the Battery Carriage House located across from beautiful White Point Gardens. Enjoy a quiet stroll along the waterfront Battery after a sumptuous meal at one of the fi...more
Doubletree Guest Suites CharlestonHistoric District
181 Church Street
Charleston, SC 29401
Nightly Rates (199.00 - 219.00)   3 Star
25.47 miles from Edisto Island Serpentarium
Doubletree Guest Suites CharlestonHistoric District Doubletree Guest Suites CharlestonHistoric District
The Doubletree Guest Suites Charleston-Historic District hotel at the corner of Church and Market Streets enjoys the most excellent location in the Charleston Historic District next to Charleston*s City Market. Our friendly Charleston hotel...more
Shem Creek Inn
1401 Shrimp Boat Lane
Mount Pleasant, SC 29464
Nightly Rates (206.10 - 229.00)   2 Star
28.18 miles from Edisto Island Serpentarium
Shem Creek Inn
All rooms recently upgraded.Rooms are decorated in sand and sea colors and offer private balconies on every room.Located on scenic shem creek/home of the local shrimping fleet/the inn is just minutes away from charleston area beaches/attrac...more
Courtyard Charleston Mt. Pleasant
1251 Woodland Ave
Mount Pleasant, SC 29464
Nightly Rates (209.00 - 209.00)   3 Star
31.19 miles from Edisto Island Serpentarium
Courtyard Charleston Mt. Pleasant Courtyard Charleston Mt. Pleasant
The award winning Courtyard Charleston Mt. Pleasant is a beautiful oasis in South Carolina's Lowcountry. We offer exceptional personal attention to our guests along with Marriott amenities and services that make business travel easier and l...more
Church Street Inn
177 Church Street
Charleston, SC 29401
Nightly Rates (209.00 - 209.00)   2 Star
25.46 miles from Edisto Island Serpentarium
Church Street Inn Church Street Inn
The Church Street Inn is a luxury all suites inn located in the heart of the historic district of Charleston, South Carolina. Our one and two bedroom units include complete kitchens, dining areas, living rooms, and 1 and 1/2 baths in a town...more
Rhett House Inn
1009 Craven St.
Beaufort, SC 29902
Nightly Rates (225.00 - 225.00)   4 Star
24.53 miles from Edisto Island Serpentarium
Rhett House Inn Rhett House Inn
Located in historic downtown Beaufort, South Carolina and a block from the Intracostal Waterway, the AAA four-diamond Rhett House is a place full of history, romance, and relaxation. Offering luxurious pleasures of an authentic plantation h...more
The Inn At Middleton Place
4920 Ashley River Road
Charleston, SC 29414
Nightly Rates (229.33 - 300.00)   2 Star
23.27 miles from Edisto Island Serpentarium
The Inn At Middleton Place The Inn At Middleton Place
Located on the bluffs of the Ashley River and secluded among tall pines and live oaks, the Inn at Middleton Place offers relaxing accommodations in an atmosphere of unsurpassed natural beauty. A recipient of the American Institute of Archit...more
Vendue Inn
19 Vendue Range
Charleston, SC 29401
Nightly Rates (233.66 - 373.00)   4 Star
25.54 miles from Edisto Island Serpentarium
Vendue Inn Vendue Inn
Imagine a place where the genteel comfort of a bygone era has been perfectly preserved. The style is more sophisticated, the service, more gracious. A place that exceeds every expectation. Youve found someplace very special at Charlestons V...more
Meeting Street Inn
173 Meeting Street
Charleston, SC 29401
Nightly Rates (241.67 - 241.67)   3 Star
25.34 miles from Edisto Island Serpentarium
Meeting Street Inn Meeting Street Inn
The Meeting Street Inn offers distinctive lodging in the heart of Charlestons historic district. Located opposite the bustling City Market the Inn is surrounded Charlestons finest restaurants boutiques and antiques shops. Everything that is...more
The Restoration on King
75 Wentworth Street
Charleston, SC 29401
Nightly Rates (265.00 - 465.00)   4 Star
25.46 miles from Edisto Island Serpentarium
The Restoration on King The Restoration on King
Experience urban lifestyle within the newly unveiled Restoration on King Hotel. Boasting 19th century architecture and minimalist design, this beautifully restored 16 room hotel is ideally located in the heart of Charleston, and overlooking...more
Charleston Harbor Resort and Marina
20 Patriots Point Rd
Mount Pleasant, SC 29464
Nightly Rates (268.33 - 479.00)   3 Star
26.98 miles from Edisto Island Serpentarium
Charleston Harbor Resort and Marina
Situated on the banks of the Charleston Harbor lies a hidden oasis. The Charleston Harbor Resort and Marina is an harbor front sanctuary that allows you to relax your mind explore your imagination indulge your senses and invites you to reli...more
Elliott House Inn
78 Queen Street
Charleston, SC 29401
Nightly Rates (269.00 - 269.00)   3 Star
25.20 miles from Edisto Island Serpentarium
Elliott House Inn
Look carefully among the gracious Georgian Federal Greek Revival Second Empire and Queen Anne style homes of historic Charleston SC and you will discover The Elliott House Inn.Historic Charlestons favorite Bed and Breakfast Inn is like Char...more
Kings Courtyard Inn
198 King Street
Charleston, SC 29401
Nightly Rates (275.00 - 300.00)  
25.25 miles from Edisto Island Serpentarium
Kings Courtyard Inn Kings Courtyard Inn
18th Century reproduction furnishings and oriental rugs. Some offer canopied beds, others feature fireplaces, and many provide views of one of the two tranquil courtyards. Located in the heart of the historic district. Just off of King and...more
Anchorage Inn Charleston
26 Vendue Range
Charleston, SC 29401
Nightly Rates (282.48 - 282.48)   2 Star
25.54 miles from Edisto Island Serpentarium
Anchorage Inn Charleston Anchorage Inn Charleston
Nestled in Charlestons historic district between the Market and Waterfront Park this English Coaching Inn will make you feel right at home. We will treat you to wine and cheese in the afternoon- sherry in the evening- turndown service with ...more
Charleston Marriott
170 Lockwood Boulevard
Charleston, SC 29403
Nightly Rates (299.00 - 324.00)   3 Star
24.40 miles from Edisto Island Serpentarium
Charleston Marriott Charleston Marriott
Rediscover your senses at one of the finest hotels Charleston, South Carolina has to offer -- Charleston Marriott! Enjoy our Charleston, South Carolina hotel's beautiful redesigned guest rooms and suites coupled with supreme service and sop...more
Market Pavilion Hotel
225 East Bay Street
Charleston, SC 29401
Nightly Rates (299.00 - 712.50)   4 Star
25.55 miles from Edisto Island Serpentarium
Market Pavilion Hotel Market Pavilion Hotel
Overview: The Market Pavilion Hotel in Charleston pairs old world charm, service and ambiance with modern comforts in a luxurious setting. Located in the heart of the largest living historic district in America, this charming boutique hotel...more
Embassy Suites Charleston Historic Charleston
337 Meeting Street
Charleston, SC 29403
Nightly Rates (309.00 - 429.00)   3 Star
25.50 miles from Edisto Island Serpentarium
Embassy Suites Charleston  Historic Charleston Embassy Suites Charleston  Historic Charleston
The Embassy Suites Historic Charleston hotel is a grand restoration of the original Citadel Military College which is listed on the National Register of Historic Buildings. This full-service upscale all-suite hotel is walking distance from ...more
The Governor's House Inn
117 Broad Street
Charleston, SC 29401
Nightly Rates (310.00 - 310.00)   4 Star
25.21 miles from Edisto Island Serpentarium
The Governor's House Inn The Governor's House Inn
Praised by one national publication as a flawless urban hideaway, Governors House is a magnificent National Historic Landmark reflecting Charlestons civility and grandeur. As Southern Living magazine discovered, Check into the Governors Hou...more
Tides Folly Beach
1 Center Street
Folly Beach, SC 29439
Nightly Rates (315.00 - 315.00)   3 Star
20.82 miles from Edisto Island Serpentarium
Tides Folly Beach Tides Folly Beach
As the only full service beachfront property in the Charleston area- Tides Folly Beach features 132 classically appointed oceanfront guest rooms-each with either one king-size bed or two double beds. Our Oceanfront Inn Rooms feature privat...more
John Rutledge House Inn
116 Broad Street
Charleston, SC 29401
Nightly Rates (322.50 - 429.00)  
25.09 miles from Edisto Island Serpentarium
John Rutledge House Inn John Rutledge House Inn
Located in the heart of the historic district. Just off of King street and approximately 4 blocks to the city market area...more
Charleston Place Hotel
205 Meeting Street
Charleston, SC 29401
Nightly Rates (355.00 - 361.00)  
25.37 miles from Edisto Island Serpentarium
Charleston Place Hotel Charleston Place Hotel
One of the finest hotels in Charleston, South Carolina, Charleston Place offers unparalleled luxury accommodations including beautifully appointed rooms and suites, award winning dining at the Palmetto Cafe and Charleston Grill restaurants,...more
Charleston Place
205 Meeting Street
Charleston, SC 29401 3133
Nightly Rates (375.00 - 2,020.00)   4 Star
26.83 miles from Edisto Island Serpentarium
Charleston Place Charleston Place
Located in the heart of Charlestons historic downtown, Charleston Place offers unparalleled luxury accommodations. The Hotel has been rated by Conde Nast Traveler as one of the top 10 Hotels in North America. Charleston Place evokes the fee...more
French Quarter Inn
166 Church Street
Charleston, SC 29401
Nightly Rates (377.10 - 419.00)   4 Star
25.45 miles from Edisto Island Serpentarium
French Quarter Inn French Quarter Inn
Overlooking The Market- Historic Rooftops And St. Philips Magnificent Steeple- The French Quarter Inn Is An Enclave Of Timeless Elegance Under The Spell Of A Peretual Moon. Guests Of The French Quarter Inn Enjoy Uncompromising Personalized ...more
Renaissance Charleston Historic District Hotel
68 Wentworth Street
Charleston, SC 29401
Nightly Rates (409.00 - 307.89)   4 Star
25.39 miles from Edisto Island Serpentarium
Renaissance Charleston Historic District Hotel Renaissance Charleston Historic District Hotel
Experience the recent transformation of our Renaissance Historic Downtown Charleston, SC hotel. Representing the newest upscale property in the city's oldest quarter, the Renaissance Charleston Historic District Hotel boasts boutique accomm...more
Wentworth Mansion
149 Wentworth Street
Charleston, SC 29401
Nightly Rates (470.00 - 560.00)  
24.95 miles from Edisto Island Serpentarium
Wentworth Mansion Wentworth Mansion
Here you will find southern hospitality at its finest in the heart of Charleston. Wentworth Mansion is the embodiment of period elegance and a brilliant example of Second Empire-style architecture, complete with a handsome mansard roof and ...more
Harbour View Inn
Two Vendue Range
Charleston, SC 29401
Nightly Rates (472.34 - 472.34)   4 Star
25.57 miles from Edisto Island Serpentarium
Harbour View Inn Harbour View Inn
Overlooking the historic harbor and waterfront park, the Harbour View Inn is Charleston's most acclaimed Inn. Surrounded by over three hundred years of history, the Harbour View Inn is within walking distance of the famous Market, world r...more
Courtyard Charleston Historic District
125 Calhoun Street
Charleston, SC 29401
Nightly Rates (499.00 - 499.00)   3 Star
25.53 miles from Edisto Island Serpentarium
Courtyard Charleston Historic District Courtyard Charleston Historic District
Courtyard by Marriott Charleston Historic District hotel in downtown Charleston is just steps from King Street boutique shopping, SPAWAR, Boeing and the Charleston Joint Base. It also boasts the largest Marriott Meeting space in the Histori...more
The Sanctuary At Kiawah Island
One Sanctuary Beach Drive
Kiawah Island, SC 29455
Nightly Rates (565.00 - 1,575.00)   4 Star
13.13 miles from Edisto Island Serpentarium
The Sanctuary At Kiawah Island The Sanctuary At Kiawah Island
The Sanctuary is designed to provide the most luxurious, oceanfront experience on the east coast. The setting is truly extraordinary in that the hotel is just 50 yards from the beautiful Kiawah Beach. The natural surroundings are both exclu...more


Edisto Island Hotel Chains